New device could improve biomarker analyses
FLOW researchers have proposed an advance in cell sorting technology that could lead to lower costs, increased accuracy and quicker analysis of biomarkers for such illnesses as cancer and malaria.
The design was proposed by the researchers at KTH Linne FLOW Centre and SeRC (Swedish e-Science Centre): Lailai Zhu, who implemented the numerical model, and Cecilia Rorai, who worked together under the guidance of Brandt and Mitra. Their work draws on numerical techniques and computational capabilities developed in the last decade to handle the complexity of microscale flows. The researchers recently published their paper in the Royal Society of Chemistry’s journal, Soft Matter.
“A particular novelty of our work is that this design process has not been done in a laboratory but as a computer simulation,” Brandt says, comparing their computer simulations to the early stages of aircraft or vehicle design. “We hope that our work will bring such a change to design of microfluidic devices, too.”
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